Product References
Perinatal murine cytomegalovirus infection reshapes the transcriptional profile and functionality of NK cells.
Nature communications
Rožmanić C,Lisnić B,Pribanić Matešić M,Mihalić A,Hiršl L,Park E,Lesac Brizić A,Indenbirken D,Viduka I,Šantić M,Adler B,Yokoyama WM,Krmpotić A,Juranić Lisnić V,Jonjić S,Brizić I
Published figure using CD49b (Integrin alpha 2) monoclonal antibody (Product # 14-5971-85) in Flow Cytometry
Thu Oct 12 00:00:00 EDT 2023
Influence of Self-MHC Class I Recognition on the Dynamics of NK Cell Responses to Cytomegalovirus Infection.
Journal of immunology (Baltimore, Md. : 1950)
Potempa M,Aguilar OA,Gonzalez-Hinojosa MDR,Tenvooren I,Marquez DM,Spitzer MH,Lanier LL
14-5971-85 was used in Mass Cytometry to suggest that restricting proliferation is the predominant effect licensing has on the NK cell population during MCMV infection, but the inhibitory Ly49-MHC interactions that take place ahead of infection contribute to their limited expansion by shrinking the pool of licensed NK cells capable of robustly responding to new challenges.
Fri Apr 01 00:00:00 EDT 2022
Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro-T cells.
The Journal of experimental medicine
Hosokawa H,Koizumi M,Masuhara K,Romero-Wolf M,Tanaka T,Nakayama T,Rothenberg EV
Published figure using CD49b (Integrin alpha 2) monoclonal antibody (Product # 14-5971-85) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Exposure to Microbial Metabolite Butyrate Prolongs the Survival Time and Changes the Growth Pattern of Human Papillomavirus 16 E6/E7-Immortalized Keratinocytes in Vivo.
The American journal of pathology
Li M,McGhee EM,Shinno L,Lee K,Lin YL
14-5971-85 was used in Immunohistochemistry to show that butyrate treatment changed the property of HPV16 E6/E7-immortalized keratinocytes.
Fri Oct 01 00:00:00 EDT 2021
Exosomes derived from retinoblastoma cells enhance tumour deterioration by infiltrating the microenvironment.
Oncology reports
Chen S,Chen X,Qiu J,Chen P,Han X,Wu Y,Zhuang J,Yang M,Wu C,Wu N,Yang Y,Ge J,Yu K,Zhuang J
14-5971-85 was used in Immunocytochemistry to reveal the role of exosomes (EXOs) from retinoblastoma cells in tumour development.
Fri Jan 01 00:00:00 EST 2021
Exosomes derived from retinoblastoma cells enhance tumour deterioration by infiltrating the microenvironment.
Oncology reports
Chen S,Chen X,Qiu J,Chen P,Han X,Wu Y,Zhuang J,Yang M,Wu C,Wu N,Yang Y,Ge J,Yu K,Zhuang J
14-5971-85 was used in Immunocytochemistry to reveal the role of exosomes (EXOs) from retinoblastoma cells in tumour development.
Fri Jan 01 00:00:00 EST 2021
In the absence of natural killer cell activation donor-specific antibody mediates chronic, but not acute, kidney allograft rejection.
Kidney international
Yagisawa T,Tanaka T,Miyairi S,Tanabe K,Dvorina N,Yokoyama WM,Valujskikh A,Baldwin WM,Fairchild RL
14-5971-85 was used in Flow Cytometry to study the consequence of high donor-specific antibody titers on kidney graft outcomes in the presence or absence of natural killer cell activation within the graft.
Fri Feb 01 00:00:00 EST 2019
Inhibition of T cell activation and function by the adaptor protein CIN85.
Science signaling
Kong MS,Hashimoto-Tane A,Kawashima Y,Sakuma M,Yokosuka T,Kometani K,Onishi R,Carpino N,Ohara O,Kurosaki T,Phua KK,Saito T
14-5971-85 was used in Flow Cytometry to show that CIN85 (Cbl-interacting protein of 85 kDa) limited T cell responses to T cell receptor stimulation.
Tue Feb 05 00:00:00 EST 2019
Glucagon-like peptide 1 receptor signaling attenuates respiratory syncytial virus-induced type 2 responses and immunopathology.
The Journal of allergy and clinical immunology
Bloodworth MH,Rusznak M,Pfister CC,Zhang J,Bastarache L,Calvillo SA,Chappell JD,Boyd KL,Toki S,Newcomb DC,Stier MT,Zhou W,Goleniewska K,Moore ML,Hartert TV,Niswender KD,Peebles RS
14-5971 was used in Flow cytometry/Cell sorting to investigate the effect of activating the GLP-1R signalling pathway on mice mimicking severe respiratory infection.
Wed Aug 01 00:00:00 EDT 2018
The Atypical Chemokine Receptor Ackr2 Constrains NK Cell Migratory Activity and Promotes Metastasis.
Journal of immunology (Baltimore, Md. : 1950)
Hansell CAH,Fraser AR,Hayes AJ,Pingen M,Burt CL,Lee KM,Medina-Ruiz L,Brownlie D,Macleod MKL,Burgoyne P,Wilson GJ,Nibbs RJB,Graham GJ
14-5971 was used in Flow cytometry/Cell sorting to determine the role of Ackr2 in metastasis.
Mon Oct 15 00:00:00 EDT 2018
CCL7 Is a Negative Regulator of Cutaneous Inflammation Following Leishmania major Infection.
Frontiers in immunology
Ford J,Hughson A,Lim K,Bardina SV,Lu W,Charo IF,Lim JK,Fowell DJ
14-5971 was used in Flow cytometry/Cell sorting to determine the role of CCL7 in Leishmania major infection.
Mon Oct 21 00:00:00 EDT 2019
Functional characterization of oxazolone-induced colitis and survival improvement by vagus nerve stimulation.
PloS one
Meroni E,Stakenborg N,Gomez-Pinilla PJ,De Hertogh G,Goverse G,Matteoli G,Verheijden S,Boeckxstaens GE
14-5971 was used in Flow cytometry/Cell sorting to characterise the immune response in oxazolone-induced colitis and study the therapeutic effect of vagus nerve stimulation.
Tue Nov 27 00:00:00 EST 2018
The transcription factor Runx3 guards cytotoxic CD8+ effector T cells against deviation towards follicular helper T cell lineage.
Nature immunology
Shan Q,Zeng Z,Xing S,Li F,Hartwig SM,Gullicksrud JA,Kurup SP,Van Braeckel-Budimir N,Su Y,Martin MD,Varga SM,Taniuchi I,Harty JT,Peng W,Badovinac VP,Xue HH
14-5971 was used in Flow cytometry/Cell sorting to show that Runx3-mediated Tcf7 repression coordinately enforced acquisition of cytotoxic functions and protected the cytotoxic lineage integrity by preventing TFH-lineage deviation.
Tue Aug 01 00:00:00 EDT 2017
NCR1-deficiency diminishes the generation of protective murine cytomegalovirus antibodies by limiting follicular helper T-cell maturation.
European journal of immunology
Miletic A,Lenartic M,Popovic B,Brizic I,Trsan T,Miklic K,Mandelboim O,Krmpotic A,Jonjic S
14-5971 was used in Flow cytometry/Cell sorting to provide evidence for the role of NCR1 in antibody response to mouse cytomegalovirus infection.
Fri Sep 01 00:00:00 EDT 2017
Identification of apoB-100 Peptide-Specific CD8+ T Cells in Atherosclerosis.
Journal of the American Heart Association
Dimayuga PC,Zhao X,Yano J,Lio WM,Zhou J,Mihailovic PM,Cercek B,Shah PK,Chyu KY
14-5971-85 was used in Flow Cytometry to identify and characterize endogenous, antigenspecific CD8+ T cells in atherosclerosis.
Sat Jul 15 00:00:00 EDT 2017
A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency.
Nature genetics
Jabara HH,Boyden SE,Chou J,Ramesh N,Massaad MJ,Benson H,Bainter W,Fraulino D,Rahimov F,Sieff C,Liu ZJ,Alshemmari SH,Al-Ramadi BK,Al-Dhekri H,Arnaout R,Abu-Shukair M,Vatsayan A,Silver E,Ahuja S,Davies EG,Sola-Visner M,Ohsumi TK,Andrews NC,Notarangelo LD,Fleming MD,Al-Herz W,Kunkel LM,Geha RS
14-5971 was used in Flow cytometry/Cell sorting to demonstrate the importance of TfR1 in adaptive immunity.
Fri Jan 01 00:00:00 EST 2016
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD49b (Integrin alpha 2) monoclonal antibody (Product # 14-5971-85) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
TAP-independent self-peptides enhance T cell recognition of immune-escaped tumors.
The Journal of clinical investigation
Doorduijn EM,Sluijter M,Querido BJ,Oliveira CC,Achour A,Ossendorp F,van der Burg SH,van Hall T
14-5971 was used in Flow cytometry/Cell sorting to analyse thymus selection and peripheral behaviour of T cells with specificity for the self-antigen known as T cell epitopes associated with impaired peptide processing (TEIPP).
Mon Feb 01 00:00:00 EST 2016
Group 2 innate lymphoid cells utilize the IRF4-IL-9 module to coordinate epithelial cell maintenance of lung homeostasis.
Mucosal immunology
Mohapatra A,Van Dyken SJ,Schneider C,Nussbaum JC,Liang HE,Locksley RM
14-5971 was used in Flow cytometry/Cell sorting to study how ILC2s link alveolar function to regulation of airway flow, revealing a key interaction between resident lymphoid and structural cells that might underlie similar organisational hierarchies in other organs.
Fri Jan 01 00:00:00 EST 2016
Blood Stem Cell Activity Is Arrested by Th1-Mediated Injury Preventing Engraftment following Nonmyeloablative Conditioning.
Journal of immunology (Baltimore, Md. : 1950)
Müller AM,Florek M,Kohrt HE,Küpper NJ,Filatenkov A,Linderman JA,Hadeiba H,Negrin RS,Shizuru JA
14-5971 was used in Flow cytometry/Cell sorting to shed new light on the effects of CD4+ T cells on HSC biology.
Tue Nov 15 00:00:00 EST 2016
Natural killer cells regulate Th1/Treg and Th17/Treg balance in chlamydial lung infection.
Journal of cellular and molecular medicine
Li J,Dong X,Zhao L,Wang X,Wang Y,Yang X,Wang H,Zhao W
14-5971 was used in Flow cytometry/Cell sorting to implicate natural killer cells role in host defence against chlamydial lung infection, through maintenance of Th1/Treg and Th17/Treg balance.
Fri Jul 01 00:00:00 EDT 2016
OASL1 deficiency promotes antiviral protection against genital herpes simplex virus type 2 infection by enhancing type I interferon production.
Scientific reports
Oh JE,Lee MS,Kim YJ,Lee HK
14-5971 was used in Flow cytometry/Cell sorting to investigate the role of 2'-5' oligoadenylate synthetase-like 1 (OASL1) during localised viral infection in mice.
Mon Jan 11 00:00:00 EST 2016
Renal F4/80+ CD11c+ mononuclear phagocytes display phenotypic and functional characteristics of macrophages in health and in adriamycin nephropathy.
Journal of the American Society of Nephrology : JASN
Cao Q,Wang Y,Wang XM,Lu J,Lee VW,Ye Q,Nguyen H,Zheng G,Zhao Y,Alexander SI,Harris DC
14-5971 was used in Flow cytometry/Cell sorting to identify the phenotype and function of renal mononuclear phagocytes expressing key markers of both macrophages and dendritic cells.
Sun Feb 01 00:00:00 EST 2015
Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells.
Frontiers in immunology
Vogel AJ,Brown DM
14-5971 was used in Flow cytometry/Cell sorting to exhibit a novel vaccine platform for inducing robust T cell responses capable of protecting against heterologous influenza A challenges.
Fri Jul 10 00:00:00 EDT 2015
Cytokine-Mediated Activation of NK Cells during Viral Infection.
Journal of virology
Freeman BE,Raué HP,Hill AB,Slifka MK
14-5971 was used in Flow cytometry/Cell sorting to study how cytokines interact to regulate natural killer cell function during viral infection.
Sat Aug 01 00:00:00 EDT 2015
Cutting edge: maresin-1 engages regulatory T cells to limit type 2 innate lymphoid cell activation and promote resolution of lung inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Krishnamoorthy N,Burkett PR,Dalli J,Abdulnour RE,Colas R,Ramon S,Phipps RP,Petasis NA,Kuchroo VK,Serhan CN,Levy BD
14-5971 was used in Flow cytometry/Cell sorting to reveal that lung MaR1 augments de novo Treg generation, and that both Tregs and MaR1 inhibit ILC2s to restrain allergic lung inflammation.
Sun Feb 01 00:00:00 EST 2015
Free ISG15 triggers an antitumor immune response against breast cancer: a new perspective.
Oncotarget
Burks J,Reed RE,Desai SD
14-5971 was used in Immunohistochemistry to provide a basis for developing strategies to increase systemic levels of free ISG15 in order to treat cancer patients overexpressing the ISG15 pathway.
Mon Mar 30 00:00:00 EDT 2015
The Gut Microbiota Reduces Colonization of the Mesenteric Lymph Nodes and IL-12-Independent IFN-γ Production During Salmonella Infection.
Frontiers in cellular and infection microbiology
Fernández-Santoscoy M,Wenzel UA,Yrlid U,Cardell S,Bäckhed F,Wick MJ
14-5971 was used in Flow cytometry/Cell sorting to study the influence of the gut microbiota during oral Salmonella infection.
Tue Jun 14 00:00:00 EDT 2016
Depletion of B220+NK1.1+ cells enhances the rejection of established melanoma by tumor-specific CD4+ T cells.
Oncoimmunology
Wilson KA,Goding SR,Neely HR,Harris KM,Antony PA
14-5971 was used in Flow cytometry/Cell sorting to show that interferon-producing killer dendritic cells are an important inhibitor of the CD4(+) T cell response to melanoma.
Sat Aug 01 00:00:00 EDT 2015
Intrinsic TGF-β signaling promotes age-dependent CD8+ T cell polyfunctionality attrition.
The Journal of clinical investigation
Bhadra R,Moretto MM,Castillo JC,Petrovas C,Ferrando-Martinez S,Shokal U,Leal M,Koup RA,Eleftherianos I,Khan IA
14-5971 was used in Flow cytometry/Cell sorting to investigate the progressive loss of CD8+ T cell polyfunctionality during aging, using animals challenged with the obligate intracellular pathogen Encephalitozoon cuniculi.
Sun Jun 01 00:00:00 EDT 2014
The Critical Role of IL-15-PI3K-mTOR Pathway in Natural Killer Cell Effector Functions.
Frontiers in immunology
Nandagopal N,Ali AK,Komal AK,Lee SH
14-5971 was used in Flow cytometry/Cell sorting to investigate whether the effect of IL-15 priming of NK cells can be extended to other cytokines, showing a critical role of the IL-15-PI3K-mTOR in NK effector functions.
Mon May 05 00:00:00 EDT 2014
Inhibition of the TRAIL death receptor by CMV reveals its importance in NK cell-mediated antiviral defense.
PLoS pathogens
Verma S,Loewendorf A,Wang Q,McDonald B,Redwood A,Benedict CA
14-5971 was used in Flow cytometry/Cell sorting to highlight the critical importance for CMV to have evolved a strategy to inhibit TRAIL-DR signaling to thwart NK-mediated defenses.
Fri Aug 01 00:00:00 EDT 2014
Characterization of conventional and atypical receptors for the chemokine CCL2 on mouse leukocytes.
Journal of immunology (Baltimore, Md. : 1950)
Ford LB,Cerovic V,Milling SW,Graham GJ,Hansell CA,Nibbs RJ
14-5971 was used in Flow cytometry/Cell sorting to define the expression profile, scavenging activity, and ligand specificity of CCL2 receptors on mouse leukocytes.
Tue Jul 01 00:00:00 EDT 2014
Murine mast cells secrete and respond to interleukin-33.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Tung HY,Plunkett B,Huang SK,Zhou Y
14-5971 was used in Flow cytometry/Cell sorting to elucidate the cellular source and regulatory mechanisms of IL-33.
Sat Mar 01 00:00:00 EST 2014
Deficiency of lymph node-resident dendritic cells (DCs) and dysregulation of DC chemoattractants in a malnourished mouse model of Leishmania donovani infection.
Infection and immunity
Ibrahim MK,Barnes JL,Osorio EY,Anstead GM,Jimenez F,Osterholzer JJ,Travi BL,Ahuja SS,White AC,Melby PC
14-5971 was used in Flow cytometry/Cell sorting to study populations of resident dendritic cells and migratory dermal dendritic cells in the skin-draining lymph nodes of L. donovani-infected malnourished mice.
Fri Aug 01 00:00:00 EDT 2014
Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells.
eLife
Sojka DK,Plougastel-Douglas B,Yang L,Pak-Wittel MA,Artyomov MN,Ivanova Y,Zhong C,Chase JM,Rothman PB,Yu J,Riley JK,Zhu J,Tian Z,Yokoyama WM
14-5971 was used in Flow cytometry/Cell sorting to investigate whether tissue-resident and cells resembling conventional splenic natural killer cells natural killer cells are derived from the same lineage, showing that there are at least four distinct lineages.
Wed Jan 01 00:00:00 EST 2014
Perivascular mast cells dynamically probe cutaneous blood vessels to capture immunoglobulin E.
Immunity
Cheng LE,Hartmann K,Roers A,Krummel MF,Locksley RM
14-5971 was used in Flow cytometry/Cell sorting to investigate the mechanism by which perivascular mast cells acquire IgE from the blood.
Thu Jan 24 00:00:00 EST 2013
Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis.
Nature immunology
Taketomi Y,Ueno N,Kojima T,Sato H,Murase R,Yamamoto K,Tanaka S,Sakanaka M,Nakamura M,Nishito Y,Kawana M,Kambe N,Ikeda K,Taguchi R,Nakamizo S,Kabashima K,Gelb MH,Arita M,Yokomizo T,Nakamura M,Watanabe K,Hirai H,Nakamura M,Okayama Y,Ra C,Aritake K,Urade Y,Morimoto K,Sugimoto Y,Shimizu T,Narumiya S,Hara S,Murakami M
14-5971 was used in Flow cytometry/Cell sorting to report that PLA2G3, a mammalian homolog of anaphylactic bee venom phospholipase A2, regulates mast cell maturation via a lipid mediator circuit.
Sat Jun 01 00:00:00 EDT 2013
Evidence for a multipotent mammary progenitor with pregnancy-specific activity.
Breast cancer research : BCR
Kaanta AS,Virtanen C,Selfors LM,Brugge JS,Neel BG
Published figure using CD49b (Integrin alpha 2) monoclonal antibody (Product # 14-5971-85) in Immunofluorescence
Mon Dec 08 00:00:00 EST 2014
A new immuno-, dystrophin-deficient model, the NSG-mdx(4Cv) mouse, provides evidence for functional improvement following allogeneic satellite cell transplantation.
Stem cells (Dayton, Ohio)
Arpke RW,Darabi R,Mader TL,Zhang Y,Toyama A,Lonetree CL,Nash N,Lowe DA,Perlingeiro RC,Kyba M
14-5971 was used in Flow cytometry/Cell sorting to highlight the potency of satellite cells to improve muscle function and the utility of the NSG-mdx(4Cv) model for studies on muscle regeneration.
Thu Aug 01 00:00:00 EDT 2013
Inflammation induced by MMP-9 enhances tumor regression of experimental breast cancer.
Journal of immunology (Baltimore, Md. : 1950)
Leifler KS,Svensson S,Abrahamsson A,Bendrik C,Robertson J,Gauldie J,Olsson AK,Dabrosin C
14-5971-85 was used immunohistochemistry (paraffin) identify matrix metalloproteinase-9 as a potent player in modulating the innate immune response into antitumour activities.
Mon Apr 15 00:00:00 EDT 2013
Critical role of SAP in progression and reactivation but not maintenance of T cell-dependent humoral immunity.
Molecular and cellular biology
Zhong MC,Veillette A
14-5971 was used in Flow cytometry/Cell sorting to explore the therapeutic potential of blocking the SLAM-associated protein (SAP) for human autoimmune diseases.
Fri Mar 01 00:00:00 EST 2013
Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells.
Immunity
Valdez PA,Vithayathil PJ,Janelsins BM,Shaffer AL,Williamson PR,Datta SK
14-5971 was used in Flow cytometry/Cell sorting to study the effect of prostaglandin E2 on the function of Th17 cells during differentiation.
Fri Apr 20 00:00:00 EDT 2012
Reverse signaling through the costimulatory ligand CD137L in epithelial cells is essential for natural killer cell-mediated acute tissue inflammation.
Proceedings of the National Academy of Sciences of the United States of America
Kim HJ,Lee JS,Kim JD,Cha HJ,Kim A,Lee SK,Lee SC,Kwon BS,Mittler RS,Cho HR,Kwon B
14-5971 was used in Flow cytometry/Cell sorting to determine the specific step at which CD137-CD137L interactions regulate renal ischemia-reperfusion injury-induced inflammation in a mouse model.
Tue Jan 03 00:00:00 EST 2012
Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection.
PLoS pathogens
Castro-Seoane R,Hummerich H,Sweeting T,Tattum MH,Linehan JM,Fernandez de Marco M,Brandner S,Collinge J,Klöhn PC
14-5971 was used in Flow cytometry/Cell sorting to study the kinetics of prion accumulation in various splenic cell types at early stages of prion infection in mice.
Wed Feb 01 00:00:00 EST 2012
The bone marrow functions as the central site of proliferation for long-lived NK cells.
Journal of immunology (Baltimore, Md. : 1950)
van Helden MJ,de Graaf N,Boog CJ,Topham DJ,Zaiss DM,Sijts AJ
14-5971 was used in Flow cytometry/Cell sorting to investigate the dynamics of natural killer cell responses after intranasal respiratory virus infection in mice.
Sat Sep 01 00:00:00 EDT 2012
Exposure to nicotine adversely affects the dendritic cell system and compromises host response to vaccination.
Journal of immunology (Baltimore, Md. : 1950)
Nouri-Shirazi M,Guinet E
14-5971 was used in Flow cytometry/Cell sorting to investigate the causal relationship between nicotine-induced dendritic cell alterations and host response to vaccines.
Thu Mar 01 00:00:00 EST 2012
CCR2 defines a distinct population of NK cells and mediates their migration during influenza virus infection in mice.
PloS one
van Helden MJ,Zaiss DM,Sijts AJ
14-5971 was used in Flow cytometry/Cell sorting to determine the role of CCR2 in NK cell migration during intranasal influenza virus infection, showing that it defines a distinct population of NK cells and mediates their migration.
Mon Jun 10 00:00:00 EDT 2013
Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance.
Oncoimmunology
Mizutani T,Neugebauer N,Putz EM,Moritz N,Simma O,Zebedin-Brandl E,Gotthardt D,Warsch W,Eckelhart E,Kantner HP,Kalinke U,Lienenklaus S,Weiss S,Strobl B,Müller M,Sexl V,Stoiber D
14-5971 was used in Flow cytometry/Cell sorting to examine the role of Type 1 IFN signalling in the prevention of leukaemogenesis.
Mon Oct 01 00:00:00 EDT 2012
Extra-thymic physiological T lineage progenitor activity is exclusively confined to cells expressing either CD127, CD90, or high levels of CD117.
PloS one
Saran N,Pommerencke J,Witzlau K,Regelin M,Krueger A
14-5971 was used in Flow cytometry/Cell sorting to suggest that a physiological thymic microenvironment does not optimally support T cell differentiation from triple negative precursors.
Mon Jun 18 00:00:00 EDT 2012
Vesicular stomatitis virus expressing tumor suppressor p53 is a highly attenuated, potent oncolytic agent.
Journal of virology
Heiber JF,Barber GN
Published figure using CD49b (Integrin alpha 2) monoclonal antibody (Product # 14-5971-85) in Western Blot
Sat Oct 01 00:00:00 EDT 2011
Identification of semaphorin 4B as a negative regulator of basophil-mediated immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Nakagawa Y,Takamatsu H,Okuno T,Kang S,Nojima S,Kimura T,Kataoka TR,Ikawa M,Toyofuku T,Katayama I,Kumanogoh A
14-5971 was used in Flow cytometry/Cell sorting to screen semaphorins for immune involvement, identifying Sema4B as a suppressor of basophil-mediated Th2-skewing.
Tue Mar 01 00:00:00 EST 2011
T cell-intrinsic factors contribute to the differential ability of CD8+ T cells to rapidly secrete IFN-γ in the absence of antigen.
Journal of immunology (Baltimore, Md. : 1950)
Bou Ghanem EN,Nelson CC,D'Orazio SE
14-5971 was used in Flow cytometry/Cell sorting to demonstrate that the microenvironment in L. monocytogenes-infected BALB/c mice is sufficient to induce responsive CD8(+) T cells to rapidly secrete IFN-γ.
Tue Feb 01 00:00:00 EST 2011
Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis.
Nature communications
Mkhikian H,Grigorian A,Li CF,Chen HL,Newton B,Zhou RW,Beeton C,Torossian S,Tatarian GG,Lee SU,Lau K,Walker E,Siminovitch KA,Chandy KG,Yu Z,Dennis JW,Demetriou M
14-5971 was used in Flow cytometry/Cell sorting to discover that genetic and the environment converge to dysregulate N-glycosylation in multiple sclerosis.
Tue Sep 20 00:00:00 EDT 2011
The interplay between surfaces and soluble factors define the immunologic and angiogenic properties of myeloid dendritic cells.
BMC immunology
Sprague L,Muccioli M,Pate M,Meles E,McGinty J,Nandigam H,Venkatesh AK,Gu MY,Mansfield K,Rutowski A,Omosebi O,Courreges MC,Benencia F
14-5971 was used in Flow cytometry/Cell sorting to study the effects of different surfaces and soluble factors on the biology of dendritic cells.
Mon Jun 06 00:00:00 EDT 2011
Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress.
Nature cell biology
Chuikov S,Levi BP,Smith ML,Morrison SJ
14-5971 was used in Flow cytometry/Cell sorting to identify genes that are preferentially expressed by stem cells and critical for their function in multiple tissues.
Fri Oct 01 00:00:00 EDT 2010
Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant.
Blood
Freire T,Zhang X,Dériaud E,Ganneau C,Vichier-Guerre S,Azria E,Launay O,Lo-Man R,Bay S,Leclerc C
14-5971 was used in Flow cytometry/Cell sorting to study dendritic cell antigen uptake and presentation by targeting the antigen receptor, macrophage galactose-type lectin (MGL), with tumor-associated Tn antigens.
Thu Nov 04 00:00:00 EDT 2010
MHC class I-deficient natural killer cells acquire a licensed phenotype after transfer into an MHC class I-sufficient environment.
The Journal of experimental medicine
Elliott JM,Wahle JA,Yokoyama WM
14-5971 was used in Flow cytometry/Cell sorting to investigate whether licensing is developmentally determined in the bone marrow, showing that MHC class I ligands are not absolutely required for licensing.
Mon Sep 27 00:00:00 EDT 2010
Murine B cells regulate serum IgE levels in a CD23-dependent manner.
Journal of immunology (Baltimore, Md. : 1950)
Cheng LE,Wang ZE,Locksley RM
14-5971 was used in Flow cytometry/Cell sorting to indicate a novel mechanism regulating serum IgE and clarify the role of CD23 in this process.
Mon Nov 01 00:00:00 EDT 2010
T-bet and eomesodermin are required for T cell-mediated antitumor immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Zhu Y,Ju S,Chen E,Dai S,Li C,Morel P,Liu L,Zhang X,Lu B
14-5971 was used in Flow cytometry/Cell sorting to define T-bet and Eomes as critical regulators of T cell-mediated immune responses against tumours.
Wed Sep 15 00:00:00 EDT 2010
Migratory and antigen presentation functions of IFN-producing killer dendritic cells.
Cancer research
Himoudi N,Yan M,Bouma G,Morgenstern D,Wallace R,Seddon B,Buddle J,Eddaoudi A,Howe SJ,Cooper N,Anderson J
14-5971 was used in Flow cytometry/Cell sorting to study how BM-IKDCs are capable of cytotoxic killing of tumour targets, and also of potent antigen presentation after encountering antigen in the context of a viable target cell.
Sat Aug 15 00:00:00 EDT 2009
Migratory and antigen presentation functions of IFN-producing killer dendritic cells.
Cancer research
Himoudi N,Yan M,Bouma G,Morgenstern D,Wallace R,Seddon B,Buddle J,Eddaoudi A,Howe SJ,Cooper N,Anderson J
14-5971 was used in Flow cytometry/Cell sorting to study how BM-IKDCs are capable of cytotoxic killing of tumour targets, and also of potent antigen presentation after encountering antigen in the context of a viable target cell.
Sat Aug 15 00:00:00 EDT 2009
Peripheral dendritic cells are essential for both the innate and adaptive antiviral immune responses in the central nervous system.
Virology
Steel CD,Hahto SM,Ciavarra RP
14-5971-85 was used in Flow Cytometry to study the adaptive primary antiviral immune response in the CNS and the effect of dendritic cells upon this in vivo.
Sat Apr 25 00:00:00 EDT 2009
In vivo expression of signaling proteins in reconstituted NK cells.
Journal of immunological methods
Orr SJ,Quigley L,McVicar DW
14-5971 was used in Flow cytometry/Cell sorting to develop a novel technique to generate NK cells in vivo, all of which express a gene of interest.
Fri Jan 30 00:00:00 EST 2009
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid.
The Journal of experimental medicine
Sun CM,Hall JA,Blank RB,Bouladoux N,Oukka M,Mora JR,Belkaid Y
14-5971 was used in Flow cytometry/Cell sorting to investigate how the intestinal immune system has evolved a self-contained strategy to promote T reg cell neoconversion.
Mon Aug 06 00:00:00 EDT 2007
The NKG2D-activating receptor mediates pulmonary clearance of Pseudomonas aeruginosa.
Infection and immunity
Borchers MT,Harris NL,Wesselkamper SC,Zhang S,Chen Y,Young L,Lau GW
14-5971 was used in Immunocytochemistry to demonstrate the importance of NKG2D-mediated immune activation in the clearance of acute bacterial infection.
Mon May 01 00:00:00 EDT 2006
-Flow-20170216130641.jpg?time=20240507 "CD49b (Integrin alpha 2) Antibody in Flow Cytometry (Flow)")
-Flow-20170216130641.jpg?time=20240507)
-Flow-20170216130641.jpg?time=20240507?time=20240507 "CD49b (Integrin alpha 2) Antibody (14-5971-85) in Flow")
